Management and Outcome of Infantile Hydrocephalus

Hydrocephalus: Hydrocephalus is a condition in which an accumulation of cerebrospinal fluid (CSF) occurs within the brain. This typically causes increased pressure inside the skull. Hydrocephalus can occur due to birth defects or be acquired later in life. Associated birth defects include neural tube defects and those that result in aqueductal stenosis. Other causes include meningitis, brain tumors, traumatic brain injury, intraventricular hemorrhage, and subarachnoid hemorrhage. The four types of hydrocephalus are communicating, […]

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Death by sulfuric acid

Chemical burns are not as common as thermal burns, but they’re just as destructive to human tissue. In this particular instance the individual committed suicide by drinking a large quantity of sulfuric acid. Sulfuric acid is particularly nasty because it’s chemical composition quickly destroys the lipid membrane of cells and denatures proteins, causing instant cellular […]

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Cardiac tamponade

Cardiac tamponade, also known as pericardial tamponade, is when fluid in the pericardium (the sac around the heart) builds up, resulting in compression of the heart. Onset may be rapid or gradual.Symptoms typically include those of cardiogenic shock including shortness of breath, weakness, lightheadedness, and cough. Other symptoms may relate to the underlying cause. Common […]

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Diaphragmatic Weakness & Paralysis

A weak or paralyzed diaphragm often goes misdiagnosed and left untreated, causing breathing issues that can worsen over time. While there are several medical treatments options, surgery remains the most effective way to treat a paralyzed or weakened diaphragm. What is the Diaphragm? The diaphragm is a large muscle that sits below the lungs and […]

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Glaucoma Awareness and Knowledge Among Ethiopians in a Tertiary Eye Care Center

Abstract Introduction Glaucoma outcomes are closely associated with patients’ awareness of the disease. However, little is known about glaucoma awareness and knowledge in Addis Ababa, a densely populated and ethnolinguistically diverse capital city in Ethiopia, the second largest country in Africa. Methods We performed a cross-sectional survey in the ophthalmology waiting room at St. Paul’s […]

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Hypertension

Hypertension or high blood pressure is a chronic medical condition in which the blood pressure in the arteries is higher than it should be. This requires the heart to work harder than normal to circulate blood through the blood vessels. Blood pressure       The pressure in the arteries  s depending on what the heart is doing. When the heart squeezes, pumping blood into the arteries, the pressure increases. When the heart relaxes, the pressure […]

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Enoxaparin

Enoxaparin sodium is an anticoagulant medication (blood thinner).[6] It is used to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) including during pregnancy and following certain types of surgery.[6] It is also used in those with acute coronary syndrome (ACS) and heart attacks.[6] It is given by injection just under the skin or into a vein.[6] It is also used during hemodialysis.[3][5] Common side effects include bleeding, fever, and swelling of the legs.[6] Bleeding […]

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Focused assessment with sonography for trauma (eFAST exam)

Focused assessment with sonography in trauma (commonly abbreviated as FAST) is a rapid bedside ultrasound examination performed by surgeons, emergency physicians, and certain paramedics as a screening test for blood around the heart (pericardial effusion) or abdominal organs (hemoperitoneum) after trauma.[1] The four classic areas that are examined for free fluid are the perihepatic space […]

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A study of glycemic variability in patients with type 2 diabetes mellitus with obstructive sleep apnea syndrome using a continuous glucose monitoring system

Clin Diabetes Endocrinol. 2020; 6: 10. Published online 2020 Jun 5. doi: 10.1186/s40842-020-00098-0 PMCID: PMC7275595 PMID: 32518676 Not applicable. Abstract Background Obstructive sleep apnea syndrome (OSAS) in association with Type 2 Diabetes Mellitus (DM) may result in increased glycemic variability affecting the glycemic control and hence increasing the risk of complications associated with diabetes. We decided […]

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Making the equivocal unequivocal: standardization of clean margins in diabetic foot osteomyelitis

Clin Diabetes Endocrinol. 2020; 6: 8. Published online 2020 May 20. doi: 10.1186/s40842-020-00096-2 PMCID: PMC7238583 PMID: 32477590 Abstract Background The prevalence of diabetes mellitus continues to rise. Diabetic foot ulcers with osteomyelitis are a diabetes-related complication presenting a significant burden to this cohort. A cure to diabetic foot osteomyelitis remains elusive and standard of care has […]

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Achieving postprandial glucose control with lixisenatide improves glycemic control in patients with type 2 diabetes on basal insulin: a post-hoc analysis of pooled data

Clin Diabetes Endocrinol. 2020; 6: 2. Published online 2020 Jan 14. doi: 10.1186/s40842-019-0088-5 PMCID: PMC6961286 PMID: 31956422 Associated Data Data Availability Statement Please contact author for data requests. Abstract Background To examine the impact on glycemic control of achieving postprandial glucose (PPG) target with lixisenatide, a once-daily glucagon-like peptide-1 receptor agonist approved in the US, in […]

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Isolated ACTH deficiency during single-agent pembrolizumab for squamous cell lung carcinoma: a case report

Clin Diabetes Endocrinol. 2020; 6: 1. Published online 2020 Jan 6. doi: 10.1186/s40842-019-0092-9 PMCID: PMC6945618 PMID: 31921440 Associated Data Data Availability Statement The data used in this current report are available from the corresponding author on reasonable request. Abstract Background The programmed cell death 1 (PD-1) inhibitor pembrolizumab is a promising agent for treatment of several […]

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The relationship between depression and risk of metabolic syndrome: a meta‐analysis of observational studies

Clin Diabetes Endocrinol. 2021; 7: 4. Published online 2021 Mar 2. doi: 10.1186/s40842-021-00117-8 PMCID: PMC7923824 PMID: 33648597 Associated Data Data Availability Statement The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request. Abstract Introduction The link between metabolic syndrome and depression has always been controversial. Different studies that […]

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Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study

Clin Diabetes Endocrinol. 2021; 7: 2. Published online 2021 Jan 5. doi: 10.1186/s40842-020-00114-3 PMCID: PMC7786902 PMID: 33402217 Associated Data Data Availability Statement Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA’s data sharing policy, including restrictions, is available at http://engagezone.msd.com/ds_documentation.php. Requests for access to the clinical study data can be […]

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Reasons for discontinuing insulin and factors associated with insulin discontinuation in patients with type 2 diabetes mellitus: a real-world evidence study

Clin Diabetes Endocrinol. 2021; 7: 1. Published online 2021 Jan 5. doi: 10.1186/s40842-020-00115-2 PMCID: PMC7786496 PMID: 33402226 Associated Data Supplementary Materials Additional file 1: Supplemental Table 1. Patient Characteristics Part II. Supplemental Table 2. Most Common Combination of Reasons for Insulin Discontinuation. 40842_2020_115_MOESM1_ESM.docx (17K) GUID: 10C9DBA6-9661-495F-9FF7-A8CCB0F801E4 Data Availability Statement The datasets generated during and/or analyzed during the […]

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Laparoscopic Bilateral Adrenalectomy in a Young Female Patient with Recurrent Cushing’s Disease

Case Rep Endocrinol. 2021; 2021: 6632436. Published online 2021 Feb 12. doi: 10.1155/2021/6632436 PMCID: PMC7895553 PMID: 33628530 Associated Data Data Availability Statement All data regarding the case are available upon request. Abstract Introduction Synchronous bilateral adrenalectomy is undertaken less often due to numerous perioperative challenges and rare circumstances of patients needing this procedure. Bilateral adrenalectomy is […]

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Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes

Case Rep Endocrinol. 2021; 2021: 6620832. Published online 2021 Feb 8. doi: 10.1155/2021/6620832 PMCID: PMC7884107 PMID: 33628529 Associated Data Data Availability Statement The data used to support the findings of this study are available from the corresponding author upon request. Abstract Ketogenic diet, a very low-carbohydrate diet and high-fat diet, has emerged as a popular approach […]

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