DIABETIC FOOT – POST INFECTIVE COMPOSITE SOFT TISSUE LOSS DORSUM FOOT

50 year old Diabetic and Hypertensive was admitted in Medical intensive care unit with infection in the foot. He was referred to plastic surgery for management of infection in the foot. He underwent surgical debridement followed by negative pressure wound therapy. followed by skin grafting. The results are shown below Patient and relatives were satifsfied […]

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A study of glycemic variability in patients with type 2 diabetes mellitus with obstructive sleep apnea syndrome using a continuous glucose monitoring system

Clin Diabetes Endocrinol. 2020; 6: 10. Published online 2020 Jun 5. doi: 10.1186/s40842-020-00098-0 PMCID: PMC7275595 PMID: 32518676 Not applicable. Abstract Background Obstructive sleep apnea syndrome (OSAS) in association with Type 2 Diabetes Mellitus (DM) may result in increased glycemic variability affecting the glycemic control and hence increasing the risk of complications associated with diabetes. We decided […]

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Making the equivocal unequivocal: standardization of clean margins in diabetic foot osteomyelitis

Clin Diabetes Endocrinol. 2020; 6: 8. Published online 2020 May 20. doi: 10.1186/s40842-020-00096-2 PMCID: PMC7238583 PMID: 32477590 Abstract Background The prevalence of diabetes mellitus continues to rise. Diabetic foot ulcers with osteomyelitis are a diabetes-related complication presenting a significant burden to this cohort. A cure to diabetic foot osteomyelitis remains elusive and standard of care has […]

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Achieving postprandial glucose control with lixisenatide improves glycemic control in patients with type 2 diabetes on basal insulin: a post-hoc analysis of pooled data

Clin Diabetes Endocrinol. 2020; 6: 2. Published online 2020 Jan 14. doi: 10.1186/s40842-019-0088-5 PMCID: PMC6961286 PMID: 31956422 Associated Data Data Availability Statement Please contact author for data requests. Abstract Background To examine the impact on glycemic control of achieving postprandial glucose (PPG) target with lixisenatide, a once-daily glucagon-like peptide-1 receptor agonist approved in the US, in […]

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Isolated ACTH deficiency during single-agent pembrolizumab for squamous cell lung carcinoma: a case report

Clin Diabetes Endocrinol. 2020; 6: 1. Published online 2020 Jan 6. doi: 10.1186/s40842-019-0092-9 PMCID: PMC6945618 PMID: 31921440 Associated Data Data Availability Statement The data used in this current report are available from the corresponding author on reasonable request. Abstract Background The programmed cell death 1 (PD-1) inhibitor pembrolizumab is a promising agent for treatment of several […]

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The relationship between depression and risk of metabolic syndrome: a meta‐analysis of observational studies

Clin Diabetes Endocrinol. 2021; 7: 4. Published online 2021 Mar 2. doi: 10.1186/s40842-021-00117-8 PMCID: PMC7923824 PMID: 33648597 Associated Data Data Availability Statement The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request. Abstract Introduction The link between metabolic syndrome and depression has always been controversial. Different studies that […]

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Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study

Clin Diabetes Endocrinol. 2021; 7: 2. Published online 2021 Jan 5. doi: 10.1186/s40842-020-00114-3 PMCID: PMC7786902 PMID: 33402217 Associated Data Data Availability Statement Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA’s data sharing policy, including restrictions, is available at http://engagezone.msd.com/ds_documentation.php. Requests for access to the clinical study data can be […]

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Reasons for discontinuing insulin and factors associated with insulin discontinuation in patients with type 2 diabetes mellitus: a real-world evidence study

Clin Diabetes Endocrinol. 2021; 7: 1. Published online 2021 Jan 5. doi: 10.1186/s40842-020-00115-2 PMCID: PMC7786496 PMID: 33402226 Associated Data Supplementary Materials Additional file 1: Supplemental Table 1. Patient Characteristics Part II. Supplemental Table 2. Most Common Combination of Reasons for Insulin Discontinuation. 40842_2020_115_MOESM1_ESM.docx (17K) GUID: 10C9DBA6-9661-495F-9FF7-A8CCB0F801E4 Data Availability Statement The datasets generated during and/or analyzed during the […]

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Laparoscopic Bilateral Adrenalectomy in a Young Female Patient with Recurrent Cushing’s Disease

Case Rep Endocrinol. 2021; 2021: 6632436. Published online 2021 Feb 12. doi: 10.1155/2021/6632436 PMCID: PMC7895553 PMID: 33628530 Associated Data Data Availability Statement All data regarding the case are available upon request. Abstract Introduction Synchronous bilateral adrenalectomy is undertaken less often due to numerous perioperative challenges and rare circumstances of patients needing this procedure. Bilateral adrenalectomy is […]

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Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes

Case Rep Endocrinol. 2021; 2021: 6620832. Published online 2021 Feb 8. doi: 10.1155/2021/6620832 PMCID: PMC7884107 PMID: 33628529 Associated Data Data Availability Statement The data used to support the findings of this study are available from the corresponding author upon request. Abstract Ketogenic diet, a very low-carbohydrate diet and high-fat diet, has emerged as a popular approach […]

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Three Successful Pregnancies in a Patient with Recurrent Cushing’s Disease

Case Rep Endocrinol. 2021; 2021: 5517303. Published online 2021 Feb 13. doi: 10.1155/2021/5517303 PMCID: PMC7899752 PMID: 33628528 Associated Data Data Availability Statement All data used in this case are available from the corresponding author upon reasonable request. Abstract The association of pregnancy and Cushing’s disease (CD) is rare. A 28-year-old woman was admitted for clinical suspicion […]

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Transient Hypophosphatemia: A Dangerous Event in Multiple Myeloma

Case Rep Endocrinol. 2021; 2021: 3609346. Published online 2021 Jan 16. doi: 10.1155/2021/3609346 PMCID: PMC7826227 PMID: 33510918 Associated Data Data Availability Statement No data were used to support this study. Abstract Patients with malignancies frequently experience multiple electrolyte disturbances. In multiple myeloma, hypercalcemia and hyperphosphatemia are one of the most common metabolic disturbances observed as part […]

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Surgical Excision of Madelung Disease Using Bilateral Cervical Lymphnode Dissection Technique—Its Effect and the Influence of Previous Injection Lipolysis

Erika Andou, MD,* Masakazu Komoto, MD,* Toshio Hasegawa, MD,† Hiroshi Mizuno, MD,* and Ayato Hayashi, MD CASE REPORT A 51-year-old man was presented to our facility with large subcutaneous tumors affecting the entire neck. Eight years earlier, he was diagnosed with Madelung disease based on the characteristic presentation of symmetrical subcutaneous tender masses throughout the […]

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Physiologic and Pharmacologic Effects of Corticosteroids

Corticosteroids are key regulators of whole-body homeostasis that provide an organism with the capacity to resist environmental changes and invasion of foreign substances. The effects of corticosteroids are widespread, including profound alterations in carbohydrate, protein, and lipid metabolism, and the modulation of electrolyte and water balance. Corticosteroids affect all of the major systems of the […]

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