Cardiology – MediHelp

Heart failure after myocardial infarction in the era of primary percutaneous coronary intervention: Mechanisms, incidence and identification of patients at risk

Thomas J Cahill and Rajesh K KharbandaWorld J Cardiol. 2017 May 26; 9(5): 407–415. Published online 2017 May 26. doi: 10.4330/wjc.v9.i5.407 PMCID: PMC5442408PMID: 28603587Received 2016 Oct 30; Revised 2017 Jan 20; Accepted 2017 Mar 12.Original source Abstract Myocardial infarction (MI) remains the most common cause of heart failure (HF) worldwide. For almost 50 years HF has been recognised as a determinant […]

Physiologic and Pharmacologic Effects of Corticosteroids

Corticosteroids are key regulators of whole-body homeostasis that provide an organism with the capacity to resist environmental changes and invasion of foreign substances. The effects of corticosteroids are widespread, including profound alterations in carbohydrate, protein, and lipid metabolism, and the modulation of electrolyte and water balance. Corticosteroids affect all of the major systems of the […]

Dietary total fat, fatty acids intake, and risk of cardiovascular disease: a dose-response meta-analysis of cohort studies

Abstract Background Several epidemiological studies have investigated the association between dietary fat intake and cardiovascular disease. However, dietary recommendations based on systematic review and meta-analysis might be more credible. Methods and results Pubmed, Embase and Cochrane library were searched up to July 1st 2018 for cohort studies reporting associations of dietary fat intake and risk […]

Neovascularization of coronary tunica intima (DIT) is the cause of coronary atherosclerosis.

1602 Samuel Drive, Madison, WI, 53717, USA Corresponding author: Vladimir M Subbotin: moc.liamg@nitobbus.m.rimidalv Background An accepted hypothesis states that coronary atherosclerosis (CA) is initiated by endothelial dysfunction due to inflammation and high levels of LDL-C, followed by deposition of lipids and macrophages from the luminal blood into the arterial intima, resulting in plaque formation. The success […]

Coronary Artery Aneurysms and Thrombosis in Kawasaki Disease

A 7-month-old male infant was brought to the hospital after being found by his foster parents to be inconsolable and crying. He was up-to-date on his immunizations and met all his developmental milestones. Significant birth history included intrauterine exposure to methamphetamine, with a positive methamphetamine drug screen at birth, and subsequent removal from his mother […]

The Accidental Invention of the Lifesaving Pacemaker

Wilson Greatbatch — who was born 100 years ago today — was tinkering with an oscilloscope in 1956 when he installed the wrong resistor and accidentally invented the implantable artificial pacemaker. Greatbatch noticed the device could be altered to drive a heartbeat and realized this was exactly what was needed to replace the bulky, painful […]

“The Ghost Heart”

Decellularization (also spelt decellularisation in British English) is the process used in biomedical engineering to isolate the extracellular matrix (ECM) of a tissue from its inhabiting cells, leaving an ECM scaffold of the original tissue, which can be used in artificial organ and tissue regeneration. Organ and tissue transplantation treat a variety of medical problems, ranging from end organ failure to cosmetic surgery. One of the greatest limitations […]