Neurons firing in real time

3D imaging of neurons from intact brain tissue. Green is to the amygdala, and purple is from the amygdala. This image is from a recent methods paper (https://www.nature.com/articles/s41467-019-09515-0#Sec15). Characterizing the precise three-dimensional morphology and anatomical context of neurons is crucial for neuronal cell type classification and circuitry mapping. Recent advances in tissue clearing techniques and […]

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History of lobotomies

On 12 November 1935, a Portuguese neurologist named Antonio Egas Moniz became the first individual to perform what would later be known as a lobotomy. Moniz’s early experiments involved drilling holes into patients’ skulls & pouring alcohol into the frontal cortex to sever nerves; and coring out regions of the brain with hollow needles. Moniz’s […]

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