Cholesterol Gallstones

Cholesterol stones are formed when the bile is supersaturated with cholesterol, which may result from decreased bile acid production, increased cholesterol output in bile or both. Stone formation by cholesterol monohydrate crystals is enhanced by mucin hypersecretion and gallbladder hypomotility. Cholesterol stone formation is promoted by conditions that increase hepatic cholesterol excretion, such as oral […]

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Physiologic and Pharmacologic Effects of Corticosteroids

Corticosteroids are key regulators of whole-body homeostasis that provide an organism with the capacity to resist environmental changes and invasion of foreign substances. The effects of corticosteroids are widespread, including profound alterations in carbohydrate, protein, and lipid metabolism, and the modulation of electrolyte and water balance. Corticosteroids affect all of the major systems of the […]

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Ruptured desmoid tumor in the jejunum

Abstract Desmoid tumors, also known as aggressive fibromatosis, are extremely rare, accounting for less than 3% of soft-tissue sarcomas and less than 0,03% of all neoplasms. The diagnosis is usually delayed because of the lack of specific symptoms, and can sometimes lead to serious and, even fatal complications. Case presentation The case report was prepared […]

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Caput medusae in alcoholic liver disease

Caput medusae is the appearance of distended and engorged superficial epigastric veins, which are seen radiating from the umbilicus across the abdomen. Case report: A 53-year-old man, with history of alcohol consumption of 60 gm/day for 20 years, presented with swelling of the legs, abdominal distension, and a collapsible localized swelling over the abdomen since 3 […]

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Ulcerative colitis in a Nigerian girl: A case report

Case presentation A 7 year old girl presented to the paediatric gastroenterology clinic at the Lagos State University Teaching Hospital (LASUTH), Ikeja with a history of prolonged diarrhoea of 10 weeks that progressed to frank haematochezia 2 weeks later. She also presented with abdominal pain weight loss of over 8 weeks duration. Stool was initially […]

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