Physiologic and Pharmacologic Effects of Corticosteroids

Corticosteroids are key regulators of whole-body homeostasis that provide an organism with the capacity to resist environmental changes and invasion of foreign substances. The effects of corticosteroids are widespread, including profound alterations in carbohydrate, protein, and lipid metabolism, and the modulation of electrolyte and water balance. Corticosteroids affect all of the major systems of the […]

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Jellyfish injuries

Lakkana Thaikruea & Potjaman Siriariyaporn  It is widely known that box jellyfish are one of the most venomous marine animals in the world [1]. Envenomation involves the physical discharge of venom into tissues. The venom is a complex mixture of polypeptides and proteins, including hemolytic, cardiotoxic and dermatonecrotic toxins The islands of Samui and Pha-ngan have the […]

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Anti-hypertension drug related Angioedema

Ian Wisecarver, Sanjay Kamboj, MD, David Galambos, Michelle Korah-Sedgwick, MD, Ross McCarron, MD, Fred Lopez, MD CASE PRESENTATION A 72 year-old African American man with a past medical history of hypertension, heart failure with reduced ejection fraction, and alcohol use presented to the emergency department (ED) with a chief complaint of a one day history […]

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Tongue Necrosis Secondary to Giant Cell Arteritis

Giant cell arteritis is a form of vasculitis involving the medium- and large-sized arteries that chiefly affects older people. Clinical findings are headache, jaw claudication, fever, pain, and thickening of the temporal artery. The most feared complication is visual loss due to impairment of the ophthalmic artery and posterior ciliary arteries. GCA occurs predominantly in […]

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Vogt–Koyanagi–Harada Syndrome – Case report

We report a 28-year-old HIV-negative Ugandan woman with no known chronic illness. She presented to the eye clinic at Mulago National Referral Hospital (Kampala, Uganda) with a 2-week history of sudden onset blurring of vision in both eyes, especially in the mornings. This was preceded by a 1-week history of low-grade intermittent fevers, sore throat, […]

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Ulcerative colitis in a Nigerian girl: A case report

Case presentation A 7 year old girl presented to the paediatric gastroenterology clinic at the Lagos State University Teaching Hospital (LASUTH), Ikeja with a history of prolonged diarrhoea of 10 weeks that progressed to frank haematochezia 2 weeks later. She also presented with abdominal pain weight loss of over 8 weeks duration. Stool was initially […]

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The kiss of death: a severe allergic reaction to a shellfish induced by a good-night kiss.

REPORT OF A CASE A 20-year-old woman presented to an emergency department of a Mayo Clinic-affiliated hospital with sudden onset of lip angioedema, throat swelling, diffuse flushing, urticaria, abdominal cramps, nausea, wheezing, severe dyspnea, and hypotension (noninvasive blood pressure level of 80/50 mm Hg) that developed immediately after kissing her boyfriend. Intramuscular diphenhydramine and methylprednisolone, […]

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