Total knee replacement

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Did you know that the first total knee replacement took place in as early as 1861?

1861: Dr. Fergusson performed resection arthroplasty of knee for arthritis.  This was followed in 1863 by Dr. Verneil with interposition arthroplasty, which inserted foreign tissue (including capsule, skin, muscle, fat chromatized pig bladder) into the joint but this technique failed to provide lasting pain control.