Carbamzepine-induced toxic epidermal necrolysis

Nithyananda K. Chowta, Mukta N. Chowta,1 John Ramapuram, Pramod Kumar,2 and Abul Fazil Case Report A 38-year-old Asian Indian male patient presented with a rapidly progressive generalized eruption with fever. Patient was diagnosed as having secondarily generalized complex partial seizures 3 weeks prior to the current illness and was prescribed carbamazepine at the dose of […]

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Extraordinary Large Giant Congenital Melanocytic Nevus Treated with Integra Dermal Regeneration Template

Kim A. Tønseth, MD, PhD,*†‡Charles Filip, MD, PhD,*†Robert Hermann, MD,*Harald Vindenes, MD,* and Hans Erik Høgevold, MD, PhD*† CASE REPORT The patient was born abroad after a normal pregnancy. Immediately after delivery, a very large voluminous GCMN of the back covering about 16% of the total body surface area and additional multiple smaller nevi on the body […]

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Neurofibromatosis type I (von Recklinghausen’s disease): A family case report and literature review

Authors: Parichehr Ghalayani,1 Zahra Saberi,2 and Farimah Sardari2 CASE REPORTS Five members of a family, a mother and her four offsprings, referred to the Department of Oral and Maxillofacial Medicine to be diagnosed and received oral and dental treatments. During clinical examination, we found clinical manifestations of neurofibromatosis in all of them. We have described all of them […]

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Conquering the odds: Cirsoid aneurysm with holocranial feeders-staged embolization, excision and grafting

Authors: Sunil Munakomi, Binod Bhattarai, and Iype Cherian A 38-year-old female presented with the complaint of slowly progressive swelling over scalp since last 20 years. There was no history of trauma, loss of consciousness, headache vomiting, altered sensorium or weakness of body parts. Surgical intervention was tried twice but abandoned due to heavy bleeding on both the occasions. […]

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Penile Kaposi’s Sarcoma

A 49-year-old man with human immunodeficiency virus (HIV) infection presented to the HIV clinic with a several-week history of multiple slow-growing, violaceous, ulcerated lesions on the glans penis and external urethral meatus. He was sexually active with male partners and had not taken prescribed antiretroviral therapy for 2 years. Laboratory studies showed a CD4 cell […]

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Progression of penile cutaneous horn to squamous cell carcinoma

Abstract The current report presents the case of a 43-year-old male suffering from a penile cutaneous horn. A surgical excision of the lesion was performed and histopathology demonstrated hyperkeratosis, dyskeratosis and epithelial hyperplasia. The cutaneous horn progressed to squamous cell carcinoma <1.5 months following surgery and a partial penectomy was conducted. The International Index of […]

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Black Market Steroid Injection Gone Wrong

CASE PRESENTATION A 35-year-old healthy man was referred to our emergency room by his physician because of painful skin necrosis over the left buttock approximately 5 × 4 cm and painful skin necrosis with purulent discharge on the right approximately 6.5 × 4 cm (Fig.1). The patient stated that he is a recreational “body builder” and uses illicit substances to rapidly […]

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Solution for skin necrosis and exposed tendon of the dorsum of the foot

Key Clinical Message For the treatment of skin necrosis with exposed tendons in rheumatoid arthritis (RA) foot, we should perform microvascular free flap surgery at an early stage without conservative treatment considering the increased risk of infection and the decreased physical activity. Keywords: dorsum of the foot, foot necrosis, friable skin, microvascular flap, treatment failure 1. INTRODUCTION […]

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Radiation recall dermatitis with soft tissue necrosis

Introduction Radiation recall dermatitis is a well known but still poorly understood inflammatory reaction that can develop in previously irradiated sites, and can be triggered by a variety of different drugs, including cytostatic agents such as gemcitabine, taxanes or anthracyclines. Two case reports of radiation recall dermatitis after administration of pemetrexed have been published, but […]

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Skin Discoloration in A Cocaine Abusing Patient

A 54-year-old woman presented with a 2-day history of a painful, enlarging rash over her face (Panel A), ears (Panel B), breasts, and extremities. Laboratory studies revealed neutropenia (neutrophil count, 1070 per cubic millimeter) and lymphopenia (lymphocyte count, 680 per cubic millimeter); the detection of antineutrophil cytoplasmic antibodies (ANCA) by immunofluorescence testing showed the perinuclear […]

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A Local Epidemic of Laced Heroin Causing Skin Necrosis

A 26-year-old female presented to our emergency department (ED) with the chief complaint of “sores on arms.” The patient was resting comfortably on the stretcher in a long sleeve jacket. She was a pleasant young woman who explained that she was an intravenous (IV) heroin drug user and that earlier that day, she had tried […]

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Successful treatment of a patient with an extraordinarily large deep burn

The patient is a 29-year-old male who was seriously burned by molten steel (about 1,500°C) from the top of the head throughout the body, in an accidental furnace explosion. Thirty hours after fluid resuscitation in a local hospital, he was referred to our hospital, when the patient was conscious and the vital signs were relatively […]

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