Case report: A 35-year-old Caucasian man with a history of chronic intravenous drug use presented to the emergency department with right upper limb pain and swelling lasting 24 hours. His initial vital signs were notable for temperature of 39°C, respiratory rate of 25 breaths per minute, heart rate of 120 beat per minute and blood […]
Read MoreAbstract Desmoid tumors, also known as aggressive fibromatosis, are extremely rare, accounting for less than 3% of soft-tissue sarcomas and less than 0,03% of all neoplasms. The diagnosis is usually delayed because of the lack of specific symptoms, and can sometimes lead to serious and, even fatal complications. Case presentation The case report was prepared […]
Read MoreThe sildenafil compound was originally developed by Pfizer for the treatment of hypertension (high blood pressure) and angina pectoris (chest pain due to heart disease). During the heart clinical trials, researchers discovered that the drug was more effective at inducing erections than treating angina. Pfizer realized ED was an unmet medical need and a major opportunity for […]
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Read MoreElephantiasis is the enlargement and hardening of limbs or body parts due to tissue swelling.[1][2] It is characterised by edema, hypertrophy, and fibrosis of skin and subcutaneous tissues, due to obstruction of lymphatic vessels.[2] It may affect the genitalia.[2] The term elephantiasis is often used in reference to (symptoms caused by) parasitic worm infections,[1][2] but may refer to variety of diseases […]
Read MoreAbstract Fregoli delusion is the mistaken belief that some person currently present in the deluded person’s environment (typically a stranger) is a familiar person in disguise. The stranger is believed to be psychologically identical to this known person (who is not present) even though the deluded person perceives the physical appearance of the stranger as […]
Read MoreA 61-year-old woman with cirrhosis was denied a liver transplant when doctors suspected she had a drinking problem. She had tested positive for alcohol use despite claiming she didn’t drink. The woman actually had a rare disorder called auto-brewery syndrome, when the body produces alcohol internally due to bacteria and yeast. It is the first-known […]
Read MoreWilson Greatbatch — who was born 100 years ago today — was tinkering with an oscilloscope in 1956 when he installed the wrong resistor and accidentally invented the implantable artificial pacemaker. Greatbatch noticed the device could be altered to drive a heartbeat and realized this was exactly what was needed to replace the bulky, painful […]
Read MoreA 49-year-old man with human immunodeficiency virus (HIV) infection presented to the HIV clinic with a several-week history of multiple slow-growing, violaceous, ulcerated lesions on the glans penis and external urethral meatus. He was sexually active with male partners and had not taken prescribed antiretroviral therapy for 2 years. Laboratory studies showed a CD4 cell […]
Read MoreDecellularization (also spelt decellularisation in British English) is the process used in biomedical engineering to isolate the extracellular matrix (ECM) of a tissue from its inhabiting cells, leaving an ECM scaffold of the original tissue, which can be used in artificial organ and tissue regeneration. Organ and tissue transplantation treat a variety of medical problems, ranging from end organ failure to cosmetic surgery. One of the greatest limitations […]
Read MoreAs soon as he stuck the needle into the newborn baby’s heel, Dr. Yashuhiro Indo knew something was wrong. “I was thinking out loud, why does this baby not cry?’” said Dr. Indo, a pediatrician and molecular geneticist from Kumamoto University. There exists a small group of people who, like this baby, have never felt […]
Read MoreAbstract Trimethylaminuria, better known as fish odor syndrome, is a psychologically disabling condition in which a patient emits a foul odor, which resembles that of rotting fish. The disorder is most commonly caused by an inherited deficiency in flavin monooxygenase 3, the vital enzyme for the metabolism of trimethylamine, which is the compound responsible for […]
Read MoreImagine walking around with a 40-pound bag of manure in your abdomen. That’s probably what life was like for the young man pictured here, who suffered from chronic constipation for most of his life. When he died in 1892 at the age of 29, an autopsy revealed that his colon was 8 feet long, with […]
Read MoreIntroduction Ovarian cysts rarely reach giant size although they are common. Cysts that reach large size may be confused with mesentery cysts, peritoneal inclusion cysts or loculated acid accumulation [1]. Mucinous tumors of the ovary account for 10% of ovarian neoplasms. Among all ovarian tumors, approximately 80% are benign, 10% are borderline and 10% are […]
Read MoreBackground Desmoid tumors (also called aggressive fibromatosis, deep musculoaponeurotic fibromatosis) are locally aggressive tumors with no potential for metastasis or dedifferentiation. Radiologically, they are usually non-specific, slow-growing solid masses that are difficult to distinguish from other soft tissue tumors, but they rarely show cystic lesions. Sporadic desmoid tumors can occur at any site in the […]
Read MoreAuthors: Alessia Giaquinta, Dovile Mociskyte, Giuseppe D’Arrigo, Giuseppe Barbagallo, Francesco Certo, Massimiliano Veroux & Pierfrancesco Veroux Case presentation A 26-year-old Libyan man was a victim of a firearm wound while he was running seeking for refuge, with a bullet penetrating his abdominal wall from the left to right side, with an entrance orifice of approximately 3 cm in diameter at the left […]
Read MoreMichael Fiechter, Alexander Ott, Jürgen Beck, Astrid Weyerbrock & Jean-Yves Fournier Case presentation A 46-year old woman initially presented with progressive orthostatic headache (sudden onset) at the emergency unit since 1 month. There was no history of trauma and the neurological exam was normal. Analgesia and bedrest, as prescribed from the patient’s family doctor, had only minor clinical effect. Initial cranial […]
Read MoreCase Report While working, a previously healthy 16-yr-old, 65-kg boy fell into a 3-m deep transport wagon being filled with whole wheat grain and was immediately submersed. Efforts to rescue him required approximately 5–7 min. He was unresponsive, cyanotic, and making spontaneous respiratory efforts on removal. During transfer by ambulance to a peripheral hospital, ventilation […]
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