Spontaneous Coronary Artery Dissection: A Rare Manifestation of Alport Syndrome

Amornpol Anuwatworn, * Prince Sethi, Kelly Steffen, Orvar Jonsson, and Marian Petrasko Abstract Alport syndrome (AS) is a genetic disorder due to inheritance of genetic mutations which lead to production of abnormal type IV collagen. AS has been associated with renal, auditory, and ocular diseases due to the presence of abnormal alpha chains of type IV collagen in the glomerulus, cochlea, […]

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Subacute Right Ventricular Perforation by Pacemaker Lead Causing Left-Sided Hemothorax and Epicardial Hematoma

Abdelrahman Ahmed, 1 Mohamed Shokr, 2 and Randy Lieberman 2 Abstract We report a case of right ventricular wall perforation by a pacemaker lead in a 78-year-old female 18 days after a permanent pacemaker insertion. This injury necessitated explant of the perforating lead and implantation of a new one with surgical backup. We review the literature and discuss the possible risk […]

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Novel Product for the Management of Coronary Ruptures Happening during Percutaneous Coronary Interventions

Case Rep Cardiol. 2021; 2021: 6688338. Published online 2021 Feb 11. doi: 10.1155/2021/6688338 PMCID: PMC7892221 PMID: 33628517 Abstract Coronary artery perforation during percutaneous coronary interventions is a rare but dreaded complication. One of the treatment methods for this complication is the injection of an obliterating material into the ruptured vessel. We will introduce a novel material […]

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Effect of Ivabradine on Left Ventricular Diastolic Function, Exercise Tolerance and Quality of Life in Patients With Heart Failure: A Systemic Review

Effect of Ivabradine on Left Ventricular Diastolic Function, Exercise Tolerance and Quality of Life in Patients With Heart Failure: A Systemic Review and Meta-Analysis of Randomized Controlled Trials Abstract Background Ivabradine is a heart rate-lowering drug that selectively inhibits the funny (If) current of the sinoatrial node. It is currently recommended in patients with heart […]

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Ventricular Fibrillation following Varicella Zoster Myocarditis

Adam Ioannou, 1 Irene Tsappa, 2 Sofia Metaxa, 3 and Constantinos G. Missouris 2 , 3 Abstract Varicella-zoster virus (VZV) infection can rarely lead to serious cardiac complications and life-threatening arrhythmias. We present a case of a 46-year-old male patient who developed VZV myocarditis and presented with recurrent syncopal episodes followed by a cardiac arrest. He had a further collapse eight years later, and […]

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Characterization of Sedentary Behavior in Heart Failure Patients With Arthritis

Abstract Background Arthritis is one of the most common comorbidities in heart failure (HF) patients, and is associated with decreased activity levels. Few studies have examined sedentary behavior (SB) in HF patients with arthritis, and little is known about the factors that may influence SB in this population. Methods This is a retrospective, secondary analysis […]

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Is Lipoprotein (a) a Risk Factor for Coronary Artery Ectasia?

Is Lipoprotein (a) a Risk Factor for Coronary Artery Ectasia? Abstract Background The pathophysiology of coronary artery ectasia (CAE) is under investigated and not well understood. Atherosclerosis is considered as the main etiologic factor for CAE in adults where more than 50% of CAE patients have atherosclerosis. Recently, lipoprotein (a) (Lp(a)) has emerged as a […]

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Heart failure after myocardial infarction in the era of primary percutaneous coronary intervention: Mechanisms, incidence and identification of patients at risk

Thomas J Cahill and Rajesh K KharbandaWorld J Cardiol. 2017 May 26; 9(5): 407–415. Published online 2017 May 26. doi: 10.4330/wjc.v9.i5.407 PMCID: PMC5442408PMID: 28603587Received 2016 Oct 30; Revised 2017 Jan 20; Accepted 2017 Mar 12.Original source Abstract Myocardial infarction (MI) remains the most common cause of heart failure (HF) worldwide. For almost 50 years HF has been recognised as a determinant […]

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Physiologic and Pharmacologic Effects of Corticosteroids

Corticosteroids are key regulators of whole-body homeostasis that provide an organism with the capacity to resist environmental changes and invasion of foreign substances. The effects of corticosteroids are widespread, including profound alterations in carbohydrate, protein, and lipid metabolism, and the modulation of electrolyte and water balance. Corticosteroids affect all of the major systems of the […]

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Dietary total fat, fatty acids intake, and risk of cardiovascular disease: a dose-response meta-analysis of cohort studies

Abstract Background Several epidemiological studies have investigated the association between dietary fat intake and cardiovascular disease. However, dietary recommendations based on systematic review and meta-analysis might be more credible. Methods and results Pubmed, Embase and Cochrane library were searched up to July 1st 2018 for cohort studies reporting associations of dietary fat intake and risk […]

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Neovascularization of coronary tunica intima (DIT) is the cause of coronary atherosclerosis.

1602 Samuel Drive, Madison, WI, 53717, USA Corresponding author: Vladimir M Subbotin: moc.liamg@nitobbus.m.rimidalv Background An accepted hypothesis states that coronary atherosclerosis (CA) is initiated by endothelial dysfunction due to inflammation and high levels of LDL-C, followed by deposition of lipids and macrophages from the luminal blood into the arterial intima, resulting in plaque formation. The success […]

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Coronary Artery Aneurysms and Thrombosis in Kawasaki Disease

A 7-month-old male infant was brought to the hospital after being found by his foster parents to be inconsolable and crying. He was up-to-date on his immunizations and met all his developmental milestones. Significant birth history included intrauterine exposure to methamphetamine, with a positive methamphetamine drug screen at birth, and subsequent removal from his mother […]

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“The Ghost Heart”

Decellularization (also spelt decellularisation in British English) is the process used in biomedical engineering to isolate the extracellular matrix (ECM) of a tissue from its inhabiting cells, leaving an ECM scaffold of the original tissue, which can be used in artificial organ and tissue regeneration. Organ and tissue transplantation treat a variety of medical problems, ranging from end organ failure to cosmetic surgery. One of the greatest limitations […]

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Successful Percutaneous Retrieval of Embolized Septal Occluder Device from Aortic Arch and Placement of a Newer Septal Occluder Device in Combined Procedure

Natraj Katta, * Sandeep Gautam, and Richard Webel Abstract Embolization of the Amplatzer Septal Occluder (ASO) device (St. Jude Medical, Minnesota) after percutaneous closure of atrial septal defect (ASD) is a rare and potentially catastrophic complication. Percutaneous retrieval of the embolized device is gaining ground as an acceptable method, although these patients are usually subsequently referred for open surgical […]

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