Some Aspects of Role of Nitric Oxide in the Mechanisms of Hypertension (Experimental Study)

Abstract Background Modulation of endothelial function is a therapeutic option to reduce some of the significant complications of hypertension. However, the relationship between endothelial dysfunction reduced nitric oxide (NO) production, and the development of hypertension is not fully understood. To establish a potential pathogenetic link between impaired NO synthesis and hypertension, we investigated the results […]

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Diffuse Alveolar Hemorrhage Induced by Vaping

Abstract There has been a significant increase in electronic cigarette (e-cigarette) use since its introduction in 2007. Ironically, there remains very few published literature on the respiratory complications of e-cigarettes. The use of personalized vaporizers or commonly known as “vaping” has started to overtake standard e-cigarette. Its dynamic vaporizer customization makes it challenging to assess […]

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HOW WWI PLAYED A KEY ROLE SHAPING PLASTIC SURGERY AND MODERN ANAESTHESIA

In 1916, young ENT surgeon Harold Gillies set up Britain’s first plastic surgery unit, where he practised the ‘strange new art’ of facial reconstruction for those who had suffered severe injuries and burns. Gillies was given the go-ahead, and by January 1916 was setting up Britain’s first plastic surgery unit at the Cambridge Military Hospital in Aldershot. Gillies toured base hospitals […]

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Association Between the Level of Low-Density Lipoprotein Cholesterol and Coronary Atherosclerosis in Patients Who Have Undergone Coronary Computed Tomography Angiography

Abstract Background Although the Japan Atherosclerosis Society Guidelines 2017 recommend lower levels of low-density lipoprotein cholesterol (LDL-C, < 70 mg/dL or ≤ 100 mg/dL) to prevent secondary cardiovascular events, we cannot conclude that a low level of LDL-C prevents primary cardiovascular events in patients with suspected coronary artery disease (CAD). Methods We registered 1,016 patients […]

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Effects of Holding Beta-Blockers on the Vital Signs of Heart Failure Patients

Background Heart failure with reduced ejection fraction (HFrEF) is associated with recurrent hospitalizations and high mortality. Guideline-directed medical therapy (GDMT) reduces morbidity, mortality and re-admission rates. Despite the evidence, less than 50% of patients with HFrEF are prescribed appropriate medical therapy. When hospitalized patients have these medications discontinued on admission or during hospitalization, they are […]

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Robot-Assisted Thoracoscopic Resection of a Posterior Mediastinal Mullerian Cyst

Calvin Chao, 1 Vijay Vanguri, 2 and Karl Uy 1 Abstract First described in 2005, the Mullerian derived cyst in the mediastinum is a rare finding with few subsequent reports. We report a case of Mullerian cyst occurring in the mediastinum of a 49-year-old female that was resected by robot-assisted thoracoscopic surgery. To our knowledge, this is the first report of […]

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China’s ‘folded man’ finds happiness and hope after life-changing surgery

Li has an autoimmune disease called ankylosing spondylitis that started when he was 18. It can cause bones to fuse, making the spine curve forward. His condition worsened over time until he was completely bent over, with three parts of his body “connected” – his chin to his chest, his breastbone to his pubic bone, […]

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A Case of Aplasia Cutis Congenita Type VI: Bart Syndrome

Yasmin Alfayez, Sahar Alsharif,* and Adel Santli Case Report A 4-h-old male newborn presented with complete absence of skin over the anteromedial aspect of both lower legs since birth. The baby was born to a 23-year-old primigravida mother via normal vaginal delivery. Both pregnancy and delivery were uncomplicated. The mother denied any history of exposure to medications or […]

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Foveal Eversion: A Possible Biomarker of Persistent Diabetic Macular Edema

Alessandro Arrigo, Emanuela Aragona, Luigi Capone, Rosangela Lattanzio, Piero Zollet, and Francesco Bandello Alessandro Arrigo Department of Ophthalmology, Scientific Institute San Raffaele Hospital, University Vita-Salute, Milan, Italy Find articles by Alessandro Arrigo Emanuela Aragona Department of Ophthalmology, Scientific Institute San Raffaele Hospital, University Vita-Salute, Milan, Italy Find articles by Emanuela Aragona Luigi Capone Department of […]

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Preliminary Observations on the Antihypertension Action of Dabigatran Etexilate in Patients With Nonvalvular Atrial Fibrillation

Preliminary Observations on the Antihypertension Action of Dabigatran Etexilate in Patients With Nonvalvular Atrial Fibrillation: A Prospective Multicenter Single-Arm Interventional Study Abstract Background In Japan, the number of patients with atrial fibrillation continues to grow with the aging of the population. Prevention of cardiogenic cerebral embolism is extremely important in patients with atrial fibrillation. While […]

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Eye Inside Out After Getting Hit By a Bull Horn

Girish S. Mishra, MS1 and Sushen Harish Bhatt, MS1 Case History A 68-year-old female, member of low socioeconomic community, presented to the casualty with history of hit over the right eye by a bull horn during her daily agricultural activities. She complained of sudden and painful loss of vision in the right eye. She also had a […]

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Effect of Complex Weight-Reducing Interventions on Rhythm Control in Obese Individuals with Atrial Fibrillation Following Catheter Ablation: A Study Protocol

Abstract Introduction Obesity and atrial fibrillation (AF) pose a significant burden on healthcare systems worldwide. Reduction of body weight has been documented to reduce the risk of AF. Little is known about the effect of different weight-reducing interventions including bariatric surgery in obese individuals on the risk of arrhythmia recurrence following catheter ablation (CA) for […]

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How does SARS-CoV-2 infection affect survival among patients with cardiovascular emergencies?

Abstract Objective A previous study revealed a preliminary trend towards higher in-hospital mortality in patients emergently admitted with acute stroke during the COVID-19 pandemic in Germany. The current study aims to further examine the possible impact of a confirmed SARS-CoV-2 infection on in-hospital mortality. Methods This was a retrospective analysis of health insurance claims data […]

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Scientists Find a Natural Protein That Stops Allergies And Autoimmune Conditions

For the millions of us plagued by hypersensitive, overactive, or downright abusive immune systems, it can feel like you’re constantly fighting your own physical self. From incessant allergies to life-threatening anaphylaxis and debilitating autoimmune disease, the system that’s supposed to be protecting us can be problematic when it goes wrong. Now, we might be closer to […]

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Reconstruction of a Missing Midface

An 18-year-old Chinese girl was referred to us with a severe facial deformity that had been present since her birth. The deformity was associated with poor speech intelligibility and feeding disturbances. Clinical examination demonstrated a severe maxillary defect and bilateral zygoma hypoplasia accompanied by nose and mandible deformities. Her mouth opening was normal, and no […]

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Esthetic Reconstruction of Complex Facial Soft Tissue Trauma

All soft tissue injuries were treated with primary intention following debridement, irrigation, and primary surgical intervention by different methods depending on the defect size and location. They explained probable complications of primary intention to all patients and informed consents were obtained from all patients before surgical interventions. The medical ethics committee of their hospital approved […]

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Necrotizing fasciitis and meningitis due to Streptococcus pneumoniae

A 68-year-old Caucasian female was admitted to our clinic, with suspected deep venous thrombosis, presenting with pain in her left calf that had lasted for 3 weeks starting after a very painful nocturnal leg cramp, and worsened over the last few days. At the time of admission, she had also experienced 5 days of malaise […]

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